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1

The local lymph node assay and the assessment of relative potency: status of validation

David A. Basketter, Frank Gerberick, Ian Kimber

Journal:

Contact Dermatitis

Year:

2007

Language:

english

File:

PDF, 143 KB

english, 2007

2

Dermal sensitization quantitative risk assessment (QRA) for fragrance ingredients

Anne Marie Api, David A. Basketter, Peter A. Cadby, Marie-France Cano, Graham Ellis, G. Frank Gerberick, Peter Griem, Pauline M. McNamee, Cindy A. Ryan, Robert Safford

Journal:

Regulatory Toxicology and Pharmacology

Year:

2008

Language:

english

File:

PDF, 770 KB

english, 2008

3

Application of the risk assessment paradigm to the induction of allergic contact dermatitis

Susan P Felter, Cindy A Ryan, David A Basketter, Nicola J Gilmour, G.Frank Gerberick

Journal:

Regulatory Toxicology and Pharmacology

Year:

2003

Language:

english

File:

PDF, 164 KB

english, 2003

4

The reduced local lymph node assay: the impact of group size

Cindy A. Ryan, Joel G. Chaney, Petra S. Kern, Grace Y. Patlewicz, David A. Basketter, Catherine J. Betts, Rebecca J. Dearman, Ian Kimber, G. Frank Gerberick

Journal:

Journal of Applied Toxicology

Year:

2008

Language:

english

File:

PDF, 204 KB

english, 2008

5

Further evaluation of the local lymph node assay in the final phase of an international collaborative trial

Scott E. Loveless, Gregory S. Ladies, G.Frank Gerberick, Cindy A. Ryan, David A. Basketter, Edward W. Scholes, Robert V. House, Jennifer Hilton, Rebecca J. Dearman, Ian Kimber

Journal:

Year:

1996

Language:

english

File:

PDF, 1.11 MB

english, 1996

6

Predictive identification of human skin sensitization thresholds

David A. Basketter, Catherine Clapp, Donna Jefferies, Bob Safford, Cindy A. Ryan, Frank Gerberick, Rebecca J. Dearman, Ian Kimber

Journal:

Contact Dermatitis

Year:

2005

Language:

english

File:

PDF, 119 KB

english, 2005

7

Mechanistic Applicability Domain Classification of a Local Lymph Node Assay Dataset for Skin Sensitization

Roberts, David W., Patlewicz, Grace, Kern, Petra S., Gerberick, Frank, Kimber, Ian, Dearman, Rebecca J., Ryan, Cindy A., Basketter, David A., Aptula, Aynur O.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 260 KB

english, 2007

8

Dose metrics in the acquisition of skin sensitization: Thresholds and importance of dose per unit area

Ian Kimber, Rebecca J. Dearman, David A. Basketter, Cindy A. Ryan, G. Frank Gerberick, Pauline M. McNamee, Jon Lalko, Anne Marie Api

Journal:

Regulatory Toxicology and Pharmacology

Year:

2008

Language:

english

File:

PDF, 132 KB

english, 2008

9

Local lymph node assay (LLNA) for detection of sensitization capacity of chemicals

G. Frank Gerberick, Cindy A. Ryan, Rebecca J. Dearman, Ian Kimber

Journal:

Year:

2007

Language:

english

File:

PDF, 139 KB

english, 2007

10

Examination of a vehicle for use with water soluble materials in the murine local lymph node assay

C.A. Ryan, L.W. Cruse, R.A. Skinner, R.J. Dearman, I. Kimber, G.F. Gerberick

Journal:

Food and Chemical Toxicology

Year:

2002

Language:

english

File:

PDF, 111 KB

english, 2002

11

[IEEE 2013 Integrated Communications, Navigation and Surveillance Conference (ICNS 2013) - Herndon, VA (2013.4.22-2013.4.25)] 2013 Integrated Communications, Navigation and Surveillance Conference (ICNS) - Predictive analytics with aviation big data

Ayhan, S., Pesce, J., Comitz, P., Sweet, D., Bliesner, S., Gerberick, G.

Year:

2013

Language:

english

File:

PDF, 629 KB

english, 2013

12

Contact allergenic potency: Correlation of human and local lymph node assay data

Journal:

American Journal of Contact Dermatitis

Year:

2001

Language:

english

File:

PDF, 128 KB

english, 2001

13

Assessing skin sensitization hazard in mice and men using non-animal test methods

Urbisch, Daniel, Mehling, Annette, Guth, Katharina, Ramirez, Tzutzuy, Honarvar, Naveed, Kolle, Susanne, Landsiedel, Robert, Jaworska, Joanna, Kern, Petra S., Gerberick, Frank, Natsch, Andreas, Emter,

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 544 KB

english, 2015

14

Compilation of Historical Local Lymph Node Data for Evaluation of Skin Sensitization Alternative Methods

Gerberick, Frank G., Ryan, Cindy A., Kern, Petra S., Schlatter, Harald, Dearman, Rebecca J., Kimber, Ian, Patlewicz, Grace Y., Basketter, David A.

Journal:

Year:

2005

Language:

english

File:

PDF, 820 KB

english, 2005

15

Application of the dermal sensitization threshold concept to chemicals classified as high potency category for skin sensitization assessment of ingredients for consumer products

Nishijo, Taku, Api, Anne Marie, Gerberick, G. Frank, Miyazawa, Masaaki, Roberts, David W., Safford, Robert J., Sakaguchi, Hitoshi

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 1.33 MB

2020

16

Determination of the relative allergenic potency of proteins: hurdles and opportunities

Krutz, Nora L., Kimber, Ian, Maurer-Stroh, Sebastian, Gerberick, G. Frank

Journal:

Critical Reviews in Toxicology

Year:

2020

File:

PDF, 1.15 MB

2020

17

Analysis of cytokine mRNA expression following repeated exposure of mice to chemical contact and respiratory allergens

E. V. Warbrick, R. J. Dearman, D. A. Basketter, G. F. Gerberick, C. A. Ryan, I. Kimber

Journal:

Journal of Applied Toxicology

Year:

1998

Language:

english

File:

PDF, 112 KB

english, 1998

18

B220 analysis with the local lymph node assay: proposal for a more flexible prediction model

Catherine J. Betts, Rebecca J. Dearman, Ian Kimber, Cindy A. Ryan, G. Frank Gerberick, Jon Lalko, Anne Marie Api

Journal:

Journal of Applied Toxicology

Year:

2007

Language:

english

File:

PDF, 101 KB

english, 2007

19

Assessment of glycosylation-dependent cell adhesion molecule 1 as a correlate of allergen-stimulated lymph node activation

Catherine J Betts, Jonathan G Moggs, Helen T Caddick, Marie Cumberbatch, George Orphanides, Rebecca J Dearman, Cindy A Ryan, Ben C Hulette, G Frank Gerberick, Ian Kimber

Journal:

Year:

2003

Language:

english

File:

PDF, 299 KB

english, 2003

20

Use of the local lymph node assay for the estimation of relative contact allergenic potency

D. A. Basketter, L. Blaikie, R. J. Dearman, I. Kimber, C. A. Ryan, G. F. Gerberick, P. Harvey, P. Evans, I. R. White, R. J. G. Rycroft

Journal:

Contact Dermatitis

Year:

2000

Language:

english

File:

PDF, 73 KB

english, 2000

21

Activity of human contact allergens in the murine local lymph node assay

C. A. Ryan, G. F. Gerberick, L. W. Cruse, D. A. Basketter, L. Lea, L. Blaikie, R. J. Dearman, E. V. Warbrick, I. Kimber

Journal:

Contact Dermatitis

Year:

2000

Language:

english

File:

PDF, 106 KB

english, 2000

22

The importance of exposure estimation in the assessment of skin sensitization risk

Michael K. Robinson, G. Frank Gerberick, Cindy A. Ryan, Pauline McNamee, Ian R. White, David A. Basketter

Journal:

Contact Dermatitis

Year:

2000

Language:

english

File:

PDF, 106 KB

english, 2000

23

The suitability of hexyl cinnamic aldehyde as a calibrant for the murine local lymph node assay

Rebecca J. Dearman, Zoe M. Wright, David A. Basketter, Cindy A. Ryan, G. Frank Gerberick, Ian Kimber

Journal:

Contact Dermatitis

Year:

2001

Language:

english

File:

PDF, 74 KB

english, 2001

24

Labelling of skin sensitizers: the new European Dangerous Preparations Directive

R. Roggeband, D. A. Basketter, A. C. De Groot, M. K. Robinson, G. F. Gerberick

Journal:

Contact Dermatitis

Year:

2001

Language:

english

File:

PDF, 69 KB

english, 2001

25

Human potency predictions for aldehydes using the local lymph node assay

David A. Basketter, Zoe M. Wright, E. Vicky Warbrick, Rebecca J. Dearman, Ian Kimber, Cindy A. Ryan, G. Frank Gerberick, Ian R. White

Journal:

Contact Dermatitis

Year:

2001

Language:

english

File:

PDF, 81 KB

english, 2001

26

Understanding fragrance allergy using an exposure-based risk assessment approach

G. Frank Gerberick, Michael K Robinson, Susan P Felter, Ian R White, David A Basketter

Journal:

Contact Dermatitis

Year:

2001

Language:

english

File:

PDF, 100 KB

english, 2001

27

A skin sensitization safety assessment of a new bleach activator technology in detergent applications

R. Roggeband, G. Helmlinger, I. Smith, K.-P. Wilhelm, C. A. Ryan, G. F. Gerberick

Journal:

Contact Dermatitis

Year:

2002

Language:

english

File:

PDF, 81 KB

english, 2002

28

Factors affecting thresholds in allergic contact dermatitis: safety and regulatory considerations

David A. Basketter, Peter Evans, G. Frank Gerberick, I. A. N. Kimber

Journal:

Contact Dermatitis

Year:

2002

Language:

english

File:

PDF, 52 KB

english, 2002

29

A review of the scientific basis for uncertainty factors for use in quantitative risk assessment for the induction of allergic contact dermatitis

Susan P. Felter, Michael K. Robinson, David A. Basketter, G. Frank Gerberick

Journal:

Contact Dermatitis

Year:

2002

Language:

english

File:

PDF, 99 KB

english, 2002

30

The local lymph node assay: past, present and future

Ian Kimber, R. J. Dearman, D. A. Basketter, C. A. Ryan, G. F. Gerberick

Journal:

Contact Dermatitis

Year:

2002

Language:

english

File:

PDF, 208 KB

english, 2002

31

Cytokine induction of a human acute myelogenous leukemia cell line (KG-1) to a CD1a+dendritic cell phenotype

B. C. Hulette, Geoffrey Rowden, Cindy A. Ryan, Cathy M. Lawson, Susan M. Dawes, Gregg M. Ridder, G. F. Gerberick

Journal:

Archives of Dermatological Research

Year:

2001

Language:

english

File:

PDF, 628 KB

english, 2001

32

Categorical QSAR models for skin sensitization based on local lymph node assay measures and both ground and excited state 4D-fingerprint descriptors

Jianzhong Liu, Petra S. Kern, G. Frank Gerberick, Osvaldo A. Santos-Filho, Emilio X. Esposito, Anton J. Hopfinger, Yufeng J. Tseng

Journal:

Journal of Computer-Aided Molecular Design

Year:

2008

Language:

english

File:

PDF, 411 KB

english, 2008

33

An international evaluation of the murine local lymph node assay and comparison of modified procedures

Ian Kimber, Jennifer Hilton, Rebecca J. Dearman, G.Frank Gerberick, Cindy A. Ryan, David A. Basketter, Edward W. Scholes, Gregory S. Ladics, Scott E. Loveless, Robert V. House, Antonio Guy

Journal:

Year:

1995

Language:

english

File:

PDF, 1.08 MB

english, 1995

34

Examination of Tetrachlorosalicylanilide (TCSA) Photoallergy Using In Vitro Photohapten-Modified Langerhans Cell-Enriched Epidermal Cells.

Gerberick, G. Frank, Ryan, Cindy A., Von Bargen, Edward C., Stuard, Sharon B., Ridder, Gregg M.

Journal:

The Journal of Investigative Dermatology

Year:

1991

File:

PDF, 5.28 MB

1991

35

Utility of historical vehicle-control data in the interpretation of the local lymph node assay

D. A. Basketter, N. J. Gilmour, D. Briggs, L. G. Ullmann, G. F. Gerberick, C. A. Ryan, R. J. Dearman, I. Kimber

Journal:

Contact Dermatitis

Year:

2003

Language:

english

File:

PDF, 75 KB

english, 2003

36

Quantitative risk assessment for the induction of allergic contact dermatitis: uncertainty factors for mucosal exposures

Miranda A. Farage, Donald L. Bjerke, Catherine Mahony, Karen L. Blackburn, G. Frank Gerberick

Journal:

Contact Dermatitis

Year:

2003

Language:

english

File:

PDF, 92 KB

english, 2003

37

A modified human repeat insult patch test for extended mucosal tissue exposure

Miranda A. Farage, Donald L. Bjerke, Catherine Mahony, Karen L. Blackburn, G. Frank Gerberick

Journal:

Contact Dermatitis

Year:

2003

Language:

english

File:

PDF, 889 KB

english, 2003

38

A chemical dataset for evaluation of alternative approaches to skin-sensitization testing

G. Frank Gerberick, Cindy A. Ryan, Petra S. Kern, Rebecca J. Dearman, Ian Kimber, Grace Y. Patlewicz, David A. Basketter

Journal:

Contact Dermatitis

Year:

2004

Language:

english

File:

PDF, 118 KB

english, 2004

39

P79 A chemical dataset for evaluation of alternative approaches to skin sensitization testing

Petra S Kern, GY Patlewicz, RJ Dearman, CA Ryan, I Kimber, DA Basketter, GF Gerberick

Journal:

Contact Dermatitis

Year:

2004

Language:

english

File:

PDF, 852 KB

english, 2004

40

P74 Categorisation of human sensitisation potency using local lymph node assay EC3 values

David A Basketter, N Gilmour, C Ryan, GF Gerberick, R Dearman, I Kimber

Journal:

Contact Dermatitis

Year:

2004

Language:

english

File:

PDF, 852 KB

english, 2004

41

PCS.04 Establishment of safe exposure limits for the induction of allergy. Theory

G Frank Gerberick, P McNamee, PS Kern, CA Ryan, DA Basketter

Journal:

Contact Dermatitis

Year:

2004

Language:

english

File:

PDF, 852 KB

english, 2004

42

Gene expression profiling in allergic contact dermatitis

Ian Kimber, RJ Dearman, CA Ryan, GF Gerberick

Journal:

Contact Dermatitis

Year:

2004

Language:

english

File:

PDF, 852 KB

english, 2004

43

Hapten–protein binding: from theory to practical application in the in vitro prediction of skin sensitization

Maja Divkovic, Camilla K. Pease, G. Frank Gerberick, David A. Basketter

Journal:

Contact Dermatitis

Year:

2005

Language:

english

File:

PDF, 177 KB

english, 2005

44

The local lymph node assay and skin sensitization: a cut-down screen to reduce animal requirements?

Ian Kimber, Rebecca J. Dearman, Catherine J. Betts, G. Frank Gerberick, Cindy A. Ryan, Petra S. Kern, Grace Y. Patlewicz, David A. Basketter

Journal:

Contact Dermatitis

Year:

2006

Language:

english

File:

PDF, 83 KB

english, 2006

45

Elicitation of the immune response to p-phenylenediamine in allergic patients: the role of dose and exposure time

C. Goebel, P.-J. Coenraads, H. Rothe, G. Kunze, M. Kock, H. Schlatter, G.F. Gerberick, B. Blömeke

Journal:

British Journal of Dermatology

Year:

2010

Language:

english

File:

PDF, 213 KB

english, 2010

46

Contact photoallergy testing of sunscreens in guinea pigs

G. Frank Gerberick, Cindy A. Ryan

Journal:

Contact Dermatitis

Year:

1989

File:

PDF, 514 KB

1989

47

An interlaboratory evaluation of the Buehler test for the identification and classification of skin sensitizers

D. A. Basketter, G. F. Gerberick

Journal:

Contact Dermatitis

Year:

1996

File:

PDF, 990 KB

1996

48

Nothing is perfect, not even the local lymph node assay: a commentary and the implications for REACH

David A. Basketter, John F. McFadden, Frank Gerberick, Amanda Cockshott, Ian Kimber

Journal:

Contact Dermatitis

Year:

2009

Language:

english

File:

PDF, 89 KB

english, 2009

49

Skin Sensitization to p-Phenylenediamine: The Diverging Roles of Oxidation and N-Acetylation for Dendritic Cell Activation and the Immune Response

Aeby, Pierre, Sieber, Thomas, Beck, Heinz, Gerberick, G Frank, Goebel, Carsten

Journal:

The Journal of Investigative Dermatology

Year:

2008

Language:

english

File:

PDF, 562 KB

english, 2008

50

Identification of Gene Expression Changes Induced by Chemical Allergens in Dendritic Cells: Opportunities for Skin Sensitization Testing

Gildea, Lucy A, Ryan, Cindy A, Foertsch, Leslie M, Kennedy, Jennifer M, Dearman, Rebecca J, Kimber, Ian, Gerberick, G Frank

Journal:

The Journal of Investigative Dermatology

Year:

2006

Language:

english

File:

PDF, 145 KB

english, 2006

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